​Within the scope of the Academic Career (Doctorate) Project on Design and Prototype Manufacturing of Safflower Harvesting Machine supported by TAGEM carried out by our institute; safflower harvesting is carried out with the effect of negative pressure (vacuum) without using any mechanical system or chemicals in harvesting with the machine. A field type harvesting machine working with a pneumatic system was made with the safflower harvesting machine and it was determined that 73% of safflower harvesting is possible with this machine. 40 times more time saving was achieved compared to human labor and 20 times more time saving was achieved compared to machines carried on backs. A patent application was made on behalf of our institute on